
Principal Software Engineer
- Company name
- Natera (website)
- Annual base salary
- $191,800 — $239,800
- Location
On-site from
- Posted on SalaryPine
About the Role
We are seeking a highly experienced and strategic-minded Principal Software Engineer or SRE to join our team. In this role, you will be a key technical leader, responsible for the architecture, development, and maintenance of our core infrastructure. Your primary mission will be to significantly enhance developer productivity and system reliability for our scientific software teams. You will tackle some of our most complex and ambiguous problems, working across multiple teams and disciplines to build the foundational technology that enables groundbreaking scientific discovery.
Responsibilities
- Infrastructure Development: Architect, design, and implement scalable, reliable, and cost-effective infrastructure solutions to support our scientific software development lifecycle.
- Developer Productivity: Identify bottlenecks and pain points in our development workflows. Build tools, automation, and platforms (e.g., CI/CD pipelines, container orchestration) that make it easier for scientists and engineers to build, test, and deploy code.
- Reliability & Performance: Act as a subject matter expert for system reliability. You will design and implement observability, monitoring, alerting, and incident response systems to ensure our critical services meet their SLAs.
- Technical Leadership: Mentor and guide other engineers, promoting best practices in software development, SRE principles, and operational excellence. You will influence technical decisions across multiple teams.
- Cross-Functional Collaboration: Partner with research scientists and software engineers to understand their unique needs and translate scientific requirements into robust, production-grade infrastructure solutions.
Required Qualifications
- Experience: 10+ years of experience in software engineering, with significant time spent in a scientific computing environment. Experience with large-scale distributed systems is a must.
- Programming & Scripting: Strong proficiency in at least one major programming language (e.g., Python, Go, Java, or C++) and scripting languages (e.g., Bash).
- Infrastructure as Code: Deep experience with tools like Terraform, CloudFormation, or Pulumi.
- Cloud Computing: Extensive hands-on experience with at least one major cloud provider (e.g., AWS, GCP, or Azure).
- Containerization & Orchestration: Expertise with Docker, Kubernetes, and Helm.
- Observability: Hands-on experience with tools for monitoring, logging, and tracing (e.g., Prometheus, Grafana, ELK stack, Datadog).
- Domain-Specific Experience: Experience with scientific computing, high-performance computing (HPC), or handling large datasets is highly desirable.
Why Join Us?
- Join a team dedicated to pushing the boundaries of scientific discovery.
- Work on problems that have a direct impact on our ability to conduct cutting-edge research.
- Opportunity to operate with a high degree of autonomy and influence the technical direction of the entire company.
- Competitive salary and benefits.
OUR OPPORTUNITY
NateraTM is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page